A Vaccine for Non-Hodgkin’s Lymphoma?   Leave a comment

House MouseThe human mammary tumor virus (HMTV), also commonly known as the “Pogo Virus,” is thought to cause breast cancer. Multiple studies have detected this virus in approximately 40% of breast cancer patients. Furthermore, a dose-response relationship has been established between “increasing levels of the virus and increasing aggressiveness of breast cancer” (Dr. Kathleen T. Ruddy’s Breast Cancer Blog). This virus is carried by house mice, and a vaccine is currently under development by Dr. Vincent Tuohy, an immunologist at the Cleveland Clinic. Animal studies demonstrated overwhelming success for his vaccine:

Tuohy’s vaccine was found to be 100% effective in preventing breast cancer in mice that received the vaccine.  In a 10-month period, none of the immunized mice developed breast cancer, whereas 100 percent of the non-immunized mice did. (Dr. Kathleen T. Ruddy’s Breast Cancer Blog)

While Dr. Tuohy’s vaccine continues to seek funding, scientists have discovered that this virus may also cause non-Hodgkin’s lymphoma (NHL). “Breast cancer patients who had the virus in their breast tumors also had it in their lymphatic tissue. Several women whose breast cancer showed evidence of the virus subsequently developed non-Hodgkin’s lymphoma” (Dr. Kathleen T. Ruddy’s Breast Cancer Blog). If Tuohy’s work enters clinical trials, those at high risk for NHL may have a new way to combat their predisposition.


Posted November 8, 2010 by lymphomactivist in Uncategorized

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